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San Francisco 49ers on Thursday Night Football

The San Francisco 49ers are 12-7 in regular-season Thursday Night Football games since 1982. San Francisco has played 19 Thursday night games in that span, winning 12 and losing 7.

49ers Thursday Night Football record: 12-7

12-7 from the 49ers’ side. Most recent: Oct 2, 2025, 49ers 26, Rams 23 at SoFi Stadium. Regular season only; ties count as ties.

Every San Francisco 49ers Thursday Night Football game

Newest first. The running record is the 49ers’ record in these games through that date. Stadiums are listed from 2000 onward.

Dateregular seasonMatchupaway at homeScorewinner firstStadiumfrom 200049ersresult · running record
Oct 2, 202549ers at Rams49ers 26, Rams 23SoFi StadiumW · 12-7
Dec 12, 2024Rams at 49ersRams 12, 49ers 6Levi's StadiumL · 11-7
Oct 10, 202449ers at Seahawks49ers 36, Seahawks 24Lumen FieldW · 11-6
Sep 21, 2023Giants at 49ers49ers 30, Giants 12Levi's StadiumW · 10-6
Dec 15, 202249ers at Seahawks49ers 21, Seahawks 13Lumen FieldW · 9-6
Dec 23, 202149ers at TitansTitans 20, 49ers 17Nissan StadiumL · 8-6
Nov 5, 2020Packers at 49ersPackers 34, 49ers 17Levi's StadiumL · 8-5
Oct 31, 201949ers at Cardinals49ers 28, Cardinals 25State Farm StadiumW · 8-4
Nov 1, 2018Raiders at 49ers49ers 34, Raiders 3Levi's StadiumW · 7-4
Sep 21, 2017Rams at 49ersRams 41, 49ers 39Levi's StadiumL · 6-4
Oct 6, 2016Cardinals at 49ersCardinals 33, 49ers 21Levi's StadiumL · 6-3
Oct 22, 2015Seahawks at 49ersSeahawks 20, 49ers 3Levi's StadiumL · 6-2
Sep 26, 201349ers at Rams49ers 35, Rams 11Edward Jones DomeW · 6-1
Oct 18, 2012Seahawks at 49ers49ers 13, Seahawks 6Candlestick ParkW · 5-1
Dec 16, 201049ers at ChargersChargers 34, 49ers 7Qualcomm StadiumL · 4-1
Nov 12, 2009Bears at 49ers49ers 10, Bears 6Candlestick ParkW · 4-0
Dec 14, 200649ers at Seahawks49ers 24, Seahawks 14Qwest FieldW · 3-0
Sep 8, 198349ers at Vikings49ers 48, Vikings 17—W · 2-0
Dec 2, 198249ers at Rams49ers 30, Rams 24—W · 1-0

San Francisco 49ers Thursday Night Football games by decade

Decadeby seasonGamesin this window49ers recordW-L-T
1980s22-0
2000s22-0
2010s84-4
2020s74-3

49ers Thursday Night Football record by opponent

Every opponent the 49ers have met in this window, most games first. Each opens the head-to-head page.

Opponentopens the head-to-headGamesin this window49ers recordW-L-T
Los Angeles Rams53-2
Seattle Seahawks54-1
Arizona Cardinals21-1
Chicago Bears11-0
Green Bay Packers10-1
Las Vegas Raiders11-0
Los Angeles Chargers10-1
Minnesota Vikings11-0
New York Giants11-0
Tennessee Titans10-1

San Francisco 49ers Thursday Night Football FAQ

When did the 49ers last play on Thursday Night Football?
Oct 2, 2025: 49ers 26, Rams 23 at SoFi Stadium.
What is the 49ers' all-time Thursday Night Football record?
12-7 in 19 games since 1982.
When did the 49ers last win on Thursday Night Football?
Oct 2, 2025: 49ers 26, Rams 23.
When did the 49ers last lose on Thursday Night Football?
Dec 12, 2024: Rams 12, 49ers 6.
Who have the 49ers played most often on Thursday Night Football?
The Los Angeles Rams and Seattle Seahawks, 5 games each; the 49ers are 3-2 against the Rams and 4-1 against the Seahawks.
What is the 49ers' longest Thursday Night Football winning streak?
4 games, from the 1982 season through the 2009 season.

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Updated: September 7, 2026 · 13,814 regular-season games in the file, 1966 to 2025