Los Angeles Chargers vs. San Francisco 49ers on Thursday Night Football
The Los Angeles Chargers are 1-0 against the San Francisco 49ers in regular-season Thursday Night Football games since 2010. The teams have met once on Thursday night in that span, with the Chargers winning 1 and San Francisco winning 0.
Chargers vs. 49ers Thursday Night Football record: 1-0
1-0 from the Chargers’ side, 0-1 from the 49ers' side. Most recent: Dec 16, 2010, Chargers 34, 49ers 7 at Qualcomm Stadium. Regular season only; ties count as ties.
Every Los Angeles Chargers vs. San Francisco 49ers Thursday Night Football game
Newest first. The running record is the Chargers’ record in these games through that date. Stadiums are listed from 2000 onward.
| Dateregular season | Matchupaway at home | Scorewinner first | Stadiumfrom 2000 | Chargersresult · running record |
|---|---|---|---|---|
| Dec 16, 2010 | 49ers at Chargers | Chargers 34, 49ers 7 | Qualcomm Stadium | W · 1-0 |
Los Angeles Chargers vs. San Francisco 49ers Thursday Night Football FAQ
- When did the Chargers and 49ers last meet on Thursday Night Football?
- Dec 16, 2010: Chargers 34, 49ers 7 at Qualcomm Stadium.
- What is the Chargers' all-time Thursday Night Football record against the 49ers?
- 1-0 in 1 game since 2010, from the Chargers' side.
- When did the Chargers last beat the 49ers on Thursday Night Football?
- Dec 16, 2010: Chargers 34, 49ers 7 at Qualcomm Stadium.
- When did the 49ers last beat the Chargers on Thursday Night Football?
- Never in these games: the 49ers are 0-1 here.
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Updated: September 7, 2026 · 13,814 regular-season games in the file, 1966 to 2025