Los Angeles Rams vs. San Francisco 49ers on Thursday Night Football
The Los Angeles Rams are 2-3 against the San Francisco 49ers in regular-season Thursday Night Football games since 1982. The teams have met 5 times on Thursday night in that span, with the Rams winning 2 and San Francisco winning 3.
Rams vs. 49ers Thursday Night Football record: 2-3
2-3 from the Rams’ side, 3-2 from the 49ers' side. Most recent: Oct 2, 2025, 49ers 26, Rams 23 at SoFi Stadium. Regular season only; ties count as ties.
Every Los Angeles Rams vs. San Francisco 49ers Thursday Night Football game
Newest first. The running record is the Rams’ record in these games through that date. Stadiums are listed from 2000 onward.
| Dateregular season | Matchupaway at home | Scorewinner first | Stadiumfrom 2000 | Ramsresult · running record |
|---|---|---|---|---|
| Oct 2, 2025 | 49ers at Rams | 49ers 26, Rams 23 | SoFi Stadium | L · 2-3 |
| Dec 12, 2024 | Rams at 49ers | Rams 12, 49ers 6 | Levi's Stadium | W · 2-2 |
| Sep 21, 2017 | Rams at 49ers | Rams 41, 49ers 39 | Levi's Stadium | W · 1-2 |
| Sep 26, 2013 | 49ers at Rams | 49ers 35, Rams 11 | Edward Jones Dome | L · 0-2 |
| Dec 2, 1982 | 49ers at Rams | 49ers 30, Rams 24 | — | L · 0-1 |
Los Angeles Rams vs. San Francisco 49ers Thursday Night Football FAQ
- When did the Rams and 49ers last meet on Thursday Night Football?
- Oct 2, 2025: 49ers 26, Rams 23 at SoFi Stadium.
- What is the Rams' all-time Thursday Night Football record against the 49ers?
- 2-3 in 5 games since 1982, from the Rams' side.
- When did the Rams last beat the 49ers on Thursday Night Football?
- Dec 12, 2024: Rams 12, 49ers 6 at Levi's Stadium.
- When did the 49ers last beat the Rams on Thursday Night Football?
- Oct 2, 2025: 49ers 26, Rams 23 at SoFi Stadium.
- What is the Rams' longest Thursday Night Football winning streak against the 49ers?
- 2 games, from the 2017 season through the 2024 season.
- What is the 49ers' longest Thursday Night Football winning streak against the Rams?
- 2 games, from the 1982 season through the 2013 season.
More: every Rams primetime and holiday game · every 49ers primetime and holiday game · Rams 2026 schedule tools · look up another pairing
Updated: September 7, 2026 · 13,814 regular-season games in the file, 1966 to 2025