San Francisco 49ers vs Tennessee Titans on Thursday Night Football
The San Francisco 49ers are 0-1 on Thursday night against the Tennessee Titans since 2021: 1 game, 0 won, 1 lost.
San Francisco 49ers vs Tennessee Titans Thursday night record since 2021
0-1 from the 49ers’ side, 1-0 from the Titans' side. Most recent: Dec 23, 2021, Titans 20, 49ers 17 at Nissan Stadium. Regular season only; ties count as ties.
Every 49ers–Titans Thursday night game
Newest first. The running record is the 49ers’ record in these games through that date. Stadiums are listed from 2000 onward.
| Dateregular season | Matchupaway at home | Scorewinner first | Stadiumfrom 2000 | 49ersresult · running record |
|---|---|---|---|---|
| Dec 23, 2021 | 49ers at Titans | Titans 20, 49ers 17 | Nissan Stadium | L · 0-1 |
San Francisco 49ers vs Tennessee Titans Thursday night FAQ
- When did the San Francisco 49ers and Tennessee Titans last meet on Thursday night?
- Dec 23, 2021: Tennessee Titans 20, San Francisco 49ers 17 at Nissan Stadium.
- What is the San Francisco 49ers' all-time Thursday night record against the Tennessee Titans?
- 0-1 in 1 game since 2021, from the San Francisco 49ers' side.
- When did the San Francisco 49ers last beat the Tennessee Titans on Thursday night?
- Never in these games: the San Francisco 49ers are 0-1 here.
- When did the Tennessee Titans last beat the San Francisco 49ers on Thursday night?
- Dec 23, 2021: Tennessee Titans 20, San Francisco 49ers 17 at Nissan Stadium.
More: every 49ers primetime and holiday game · every Titans primetime and holiday game · 49ers 2026 schedule tools · look up another pairing
Updated: September 7, 2026 · 13,814 regular-season games in the file, 1966 to 2025