Arizona Cardinals vs. San Francisco 49ers on Thursday Night Football
The Arizona Cardinals are 1-1 against the San Francisco 49ers in regular-season Thursday Night Football games since 2016. The teams have met twice on Thursday night in that span, with Arizona winning 1 and San Francisco winning 1.
Cardinals vs. 49ers Thursday Night Football record: 1-1
1-1 from the Cardinals’ side, 1-1 from the 49ers' side. Most recent: Oct 31, 2019, 49ers 28, Cardinals 25 at State Farm Stadium. Regular season only; ties count as ties.
Every Arizona Cardinals vs. San Francisco 49ers Thursday Night Football game
Newest first. The running record is the Cardinals’ record in these games through that date. Stadiums are listed from 2000 onward.
| Dateregular season | Matchupaway at home | Scorewinner first | Stadiumfrom 2000 | Cardinalsresult · running record |
|---|---|---|---|---|
| Oct 31, 2019 | 49ers at Cardinals | 49ers 28, Cardinals 25 | State Farm Stadium | L · 1-1 |
| Oct 6, 2016 | Cardinals at 49ers | Cardinals 33, 49ers 21 | Levi's Stadium | W · 1-0 |
Arizona Cardinals vs. San Francisco 49ers Thursday Night Football FAQ
- When did the Cardinals and 49ers last meet on Thursday Night Football?
- Oct 31, 2019: 49ers 28, Cardinals 25 at State Farm Stadium.
- What is the Cardinals' all-time Thursday Night Football record against the 49ers?
- 1-1 in 2 games since 2016, from the Cardinals' side.
- When did the Cardinals last beat the 49ers on Thursday Night Football?
- Oct 6, 2016: Cardinals 33, 49ers 21 at Levi's Stadium.
- When did the 49ers last beat the Cardinals on Thursday Night Football?
- Oct 31, 2019: 49ers 28, Cardinals 25 at State Farm Stadium.
More: every Cardinals primetime and holiday game · every 49ers primetime and holiday game · Cardinals 2026 schedule tools · look up another pairing
Updated: September 7, 2026 · 13,814 regular-season games in the file, 1966 to 2025