MOCKSLATE

Has an NFL game ever ended 49–21?

Yes. 49–21 has been an NFL final score 12 times, most recently Saints 49, Rams 21 on November 27, 2016. It first happened on October 17, 1954, the 473rd different final score the league had produced.

Every NFL game that ended 49–21

Datenewest firstWinner49 pointsLoser21 pointsWherehome teamRoundplayoffsWindowstandalone game
Nov 27, 2016New Orleans SaintsLos Angeles RamsSaints——
Jan 1, 2012New England PatriotsBuffalo BillsPatriots——
Oct 30, 2005Denver BroncosPhiladelphia EaglesBroncos——
Nov 15, 2004Philadelphia EaglesDallas CowboysCowboys—Monday Night Football
Sep 8, 2002Miami DolphinsDetroit LionsDolphins——
Oct 31, 1971Los Angeles ChargersNew York JetsChargers——
Dec 10, 1961Kansas City ChiefsDenver BroncosChiefs——
Oct 4, 1959Philadelphia EaglesNew York GiantsEagles——
Sep 27, 1959Arizona CardinalsWashington CommandersCardinals——
Nov 16, 1958Philadelphia EaglesArizona CardinalsEagles——
Dec 16, 1956Los Angeles RamsGreen Bay PackersRams——
Oct 17, 1954Philadelphia EaglesWashington CommandersCommanders——

Scores next to 49–21

Where 49–21 sits

49–21 was the 473rd different final score in NFL history, and it first happened in 1954. The league has produced 1,097 different final scores through 18,340 games. See the whole grid →

About the data

Scorigami is a term coined by Jon Bois in 2014; his 2016 video explains the idea. Game data from nflverse and the FiveThirtyEight NFL archive: every NFL and AFL regular-season and playoff game since 1920, Super Bowls included, the AAFC and the Pro Bowl left out. Franchises carry their current name, so the Baltimore Colts count for Indianapolis and the Houston Oilers for Tennessee.

Updated: October 26, 2026