Has an NFL game ever ended 41–22?
Yes. 41–22 has been an NFL final score 4 times, most recently 49ers 41, Cardinals 22 on November 16, 2025. It first happened on October 11, 1987, the 811th different final score the league had produced.
Every NFL game that ended 41–22
| Datenewest first | Winner41 points | Loser22 points | Wherehome team | Roundplayoffs | Windowstandalone game |
|---|---|---|---|---|---|
| Nov 16, 2025 | San Francisco 49ers | Arizona Cardinals | Cardinals | — | — |
| Dec 5, 2021 | Los Angeles Chargers | Cincinnati Bengals | Bengals | — | — |
| Dec 24, 1995 | Miami Dolphins | Los Angeles Rams | Rams | — | — |
| Oct 11, 1987 | Dallas Cowboys | Philadelphia Eagles | Cowboys | — | — |
Scores next to 41–22
Where 41–22 sits
41–22 was the 811th different final score in NFL history, and it first happened in 1987. The league has produced 1,097 different final scores through 18,340 games. See the whole grid →
About the data
Scorigami is a term coined by Jon Bois in 2014; his 2016 video explains the idea. Game data from nflverse and the FiveThirtyEight NFL archive: every NFL and AFL regular-season and playoff game since 1920, Super Bowls included, the AAFC and the Pro Bowl left out. Franchises carry their current name, so the Baltimore Colts count for Indianapolis and the Houston Oilers for Tennessee.
Updated: October 26, 2026