MOCKSLATE

Has an NFL game ever ended 41–22?

41–22 has been an NFL final score 4 times, most recently 49ers 41, Cardinals 22 on November 16, 2025. It first happened on October 11, 1987, unique score number 811 in NFL history.

Every NFL game that ended 41–22

Datenewest firstWinner41 pointsLoser22 pointsWherehome teamRoundplayoffsWindowstandalone game
Nov 16, 2025San Francisco 49ersArizona CardinalsCardinals
Dec 5, 2021Los Angeles ChargersCincinnati BengalsBengals
Dec 24, 1995Miami DolphinsLos Angeles RamsRams
Oct 11, 1987Dallas CowboysPhiladelphia EaglesCowboys

Scores next to 41–22

Where 41–22 sits

41–22 was the 811th unique final score in NFL history, first seen in 1987. The league has produced 1,095 unique scores through 18,234 games. See the whole grid →

About the data

Scorigami is a term coined by Jon Bois in 2014; his 2016 video explains the idea. Game data from nflverse and the FiveThirtyEight NFL archive: every NFL and AFL regular-season and playoff game since 1920, Super Bowls included, the AAFC and the Pro Bowl left out. Franchises carry their current name, so the Baltimore Colts count for Indianapolis and the Houston Oilers for Tennessee.

Updated: September 9, 2026