Has an NFL game ever ended 43–22?

Yes, once. The Patriots beat the Colts 43–22 on January 11, 2014. It was unique score number 1,015 in NFL history.

Every NFL game that ended 43–22

Datenewest first	Winner43 points	Loser22 points	Wherehome team	Roundplayoffs	Windowstandalone game
Jan 11, 2014	New England Patriots	Indianapolis Colts	Patriots	Divisional	—

Scores next to 43–22

42–21 happened 25 times
42–22 happened once
42–23 happened 5 times
43–21 happened 3 times
43–23 happened 3 times
44–21 happened 9 times
44–22 happened 4 times
44–23 happened 4 times

Where 43–22 sits

43–22 was the 1015th unique final score in NFL history, first seen in 2013. The league has produced 1,095 unique scores through 18,234 games. See the whole grid →

About the data

Scorigami is a term coined by Jon Bois in 2014; his 2016 video explains the idea. Game data from nflverse and the FiveThirtyEight NFL archive: every NFL and AFL regular-season and playoff game since 1920, Super Bowls included, the AAFC and the Pro Bowl left out. Franchises carry their current name, so the Baltimore Colts count for Indianapolis and the Houston Oilers for Tennessee.

Updated: September 9, 2026