MOCKSLATE

Has an NFL game ever ended 43–21?

43–21 has been an NFL final score 3 times, most recently Bills 43, Commanders 21 on September 26, 2021. It first happened on September 23, 1960, unique score number 516 in NFL history.

Every NFL game that ended 43–21

Datenewest firstWinner43 pointsLoser21 pointsWherehome teamRoundplayoffsWindowstandalone game
Sep 26, 2021Buffalo BillsWashington CommandersBills
Nov 2, 2014New England PatriotsDenver BroncosPatriots
Sep 23, 1960Arizona CardinalsLos Angeles RamsRams

Scores next to 43–21

Where 43–21 sits

43–21 was the 516th unique final score in NFL history, first seen in 1960. The league has produced 1,095 unique scores through 18,234 games. See the whole grid →

About the data

Scorigami is a term coined by Jon Bois in 2014; his 2016 video explains the idea. Game data from nflverse and the FiveThirtyEight NFL archive: every NFL and AFL regular-season and playoff game since 1920, Super Bowls included, the AAFC and the Pro Bowl left out. Franchises carry their current name, so the Baltimore Colts count for Indianapolis and the Houston Oilers for Tennessee.

Updated: September 9, 2026