New Orleans Saints vs. San Francisco 49ers on Monday Night Football
The New Orleans Saints are 1-4 against the San Francisco 49ers in regular-season Monday Night Football games since 1989. The teams have met 5 times on Monday night in that span, with New Orleans winning 1 and San Francisco winning 4.
Saints vs. 49ers Monday Night Football record: 1-4
1-4 from the Saints’ side, 4-1 from the 49ers' side. Most recent: Sep 20, 2010, Saints 25, 49ers 22 at Candlestick Park. Regular season only; ties count as ties.
Every New Orleans Saints vs. San Francisco 49ers Monday Night Football game
Newest first. The running record is the Saints’ record in these games through that date. Stadiums are listed from 2000 onward.
| Dateregular season | Matchupaway at home | Scorewinner first | Stadiumfrom 2000 | Saintsresult · running record |
|---|---|---|---|---|
| Sep 20, 2010 | Saints at 49ers | Saints 25, 49ers 22 | Candlestick Park | W · 1-4 |
| Nov 28, 1994 | 49ers at Saints | 49ers 35, Saints 14 | — | L · 0-4 |
| Nov 22, 1993 | Saints at 49ers | 49ers 42, Saints 7 | — | L · 0-3 |
| Sep 10, 1990 | 49ers at Saints | 49ers 13, Saints 12 | — | L · 0-2 |
| Nov 6, 1989 | Saints at 49ers | 49ers 31, Saints 13 | — | L · 0-1 |
New Orleans Saints vs. San Francisco 49ers Monday Night Football FAQ
- When did the Saints and 49ers last meet on Monday Night Football?
- Sep 20, 2010: Saints 25, 49ers 22 at Candlestick Park.
- What is the Saints' all-time Monday Night Football record against the 49ers?
- 1-4 in 5 games since 1989, from the Saints' side.
- When did the Saints last beat the 49ers on Monday Night Football?
- Sep 20, 2010: Saints 25, 49ers 22 at Candlestick Park.
- When did the 49ers last beat the Saints on Monday Night Football?
- Nov 28, 1994: 49ers 35, Saints 14.
- What is the 49ers' longest Monday Night Football winning streak against the Saints?
- 4 games, from the 1989 season through the 1994 season.
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Updated: September 7, 2026 · 13,814 regular-season games in the file, 1966 to 2025