Los Angeles Rams vs San Francisco 49ers on Monday Night Football
The Los Angeles Rams are 4-8 on Monday night against the San Francisco 49ers since 1972: 12 games, 4 won, 8 lost.
Los Angeles Rams vs San Francisco 49ers Monday night record since 1972
4-8 from the Rams’ side, 8-4 from the 49ers' side. Most recent: Oct 3, 2022, 49ers 24, Rams 9 at Levi's Stadium. Regular season only; ties count as ties.
Every Rams–49ers Monday night game
Newest first. The running record is the Rams’ record in these games through that date. Stadiums are listed from 2000 onward.
| Dateregular season | Matchupaway at home | Scorewinner first | Stadiumfrom 2000 | Ramsresult · running record |
|---|---|---|---|---|
| Oct 3, 2022 | Rams at 49ers | 49ers 24, Rams 9 | Levi's Stadium | L · 4-8 |
| Nov 15, 2021 | Rams at 49ers | 49ers 31, Rams 10 | Levi's Stadium | L · 4-7 |
| Sep 12, 2016 | Rams at 49ers | 49ers 28, Rams 0 | Levi's Stadium | L · 4-6 |
| Oct 13, 2014 | 49ers at Rams | 49ers 31, Rams 17 | Edward Jones Dome | L · 4-5 |
| Dec 30, 2002 | 49ers at Rams | Rams 31, 49ers 20 | Edward Jones Dome | W · 4-4 |
| Nov 25, 1991 | 49ers at Rams | 49ers 33, Rams 10 | — | L · 3-4 |
| Dec 17, 1990 | 49ers at Rams | 49ers 26, Rams 10 | — | L · 3-3 |
| Dec 11, 1989 | 49ers at Rams | 49ers 30, Rams 27 | — | L · 3-2 |
| Dec 9, 1985 | Rams at 49ers | Rams 27, 49ers 20 | — | W · 3-1 |
| Oct 11, 1976 | 49ers at Rams | 49ers 16, Rams 0 | — | L · 2-1 |
| Nov 4, 1974 | Rams at 49ers | Rams 15, 49ers 13 | — | W · 2-0 |
| Dec 4, 1972 | Rams at 49ers | Rams 26, 49ers 16 | — | W · 1-0 |
Los Angeles Rams vs San Francisco 49ers Monday night games by decade
| Decadeby season | Gamesin this window | Rams recordW-L-T |
|---|---|---|
| 1970s | 3 | 2-1 |
| 1980s | 2 | 1-1 |
| 1990s | 2 | 0-2 |
| 2000s | 1 | 1-0 |
| 2010s | 2 | 0-2 |
| 2020s | 2 | 0-2 |
Los Angeles Rams vs San Francisco 49ers Monday night FAQ
- When did the Los Angeles Rams and San Francisco 49ers last meet on Monday night?
- Oct 3, 2022: San Francisco 49ers 24, Los Angeles Rams 9 at Levi's Stadium.
- What is the Los Angeles Rams' all-time Monday night record against the San Francisco 49ers?
- 4-8 in 12 games since 1972, from the Los Angeles Rams' side.
- When did the Los Angeles Rams last beat the San Francisco 49ers on Monday night?
- Dec 30, 2002: Los Angeles Rams 31, San Francisco 49ers 20 at Edward Jones Dome.
- When did the San Francisco 49ers last beat the Los Angeles Rams on Monday night?
- Oct 3, 2022: San Francisco 49ers 24, Los Angeles Rams 9 at Levi's Stadium.
More: every Rams primetime and holiday game · every 49ers primetime and holiday game · Rams 2026 schedule tools · look up another pairing
Updated: September 7, 2026 · 13,814 regular-season games in the file, 1966 to 2025