Los Angeles Rams vs. San Francisco 49ers on Monday Night Football
The Los Angeles Rams are 4-8 against the San Francisco 49ers in regular-season Monday Night Football games since 1972. The teams have met 12 times on Monday night in that span, with the Rams winning 4 and San Francisco winning 8.
Rams vs. 49ers Monday Night Football record: 4-8
4-8 from the Rams’ side, 8-4 from the 49ers' side. Most recent: Oct 3, 2022, 49ers 24, Rams 9 at Levi's Stadium. Regular season only; ties count as ties.
Every Los Angeles Rams vs. San Francisco 49ers Monday Night Football game
Newest first. The running record is the Rams’ record in these games through that date. Stadiums are listed from 2000 onward.
| Dateregular season | Matchupaway at home | Scorewinner first | Stadiumfrom 2000 | Ramsresult · running record |
|---|---|---|---|---|
| Oct 3, 2022 | Rams at 49ers | 49ers 24, Rams 9 | Levi's Stadium | L · 4-8 |
| Nov 15, 2021 | Rams at 49ers | 49ers 31, Rams 10 | Levi's Stadium | L · 4-7 |
| Sep 12, 2016 | Rams at 49ers | 49ers 28, Rams 0 | Levi's Stadium | L · 4-6 |
| Oct 13, 2014 | 49ers at Rams | 49ers 31, Rams 17 | Edward Jones Dome | L · 4-5 |
| Dec 30, 2002 | 49ers at Rams | Rams 31, 49ers 20 | Edward Jones Dome | W · 4-4 |
| Nov 25, 1991 | 49ers at Rams | 49ers 33, Rams 10 | — | L · 3-4 |
| Dec 17, 1990 | 49ers at Rams | 49ers 26, Rams 10 | — | L · 3-3 |
| Dec 11, 1989 | 49ers at Rams | 49ers 30, Rams 27 | — | L · 3-2 |
| Dec 9, 1985 | Rams at 49ers | Rams 27, 49ers 20 | — | W · 3-1 |
| Oct 11, 1976 | 49ers at Rams | 49ers 16, Rams 0 | — | L · 2-1 |
| Nov 4, 1974 | Rams at 49ers | Rams 15, 49ers 13 | — | W · 2-0 |
| Dec 4, 1972 | Rams at 49ers | Rams 26, 49ers 16 | — | W · 1-0 |
Los Angeles Rams vs. San Francisco 49ers Monday Night Football games by decade
| Decadeby season | Gamesin this window | Rams recordW-L-T |
|---|---|---|
| 1970s | 3 | 2-1 |
| 1980s | 2 | 1-1 |
| 1990s | 2 | 0-2 |
| 2000s | 1 | 1-0 |
| 2010s | 2 | 0-2 |
| 2020s | 2 | 0-2 |
Los Angeles Rams vs. San Francisco 49ers Monday Night Football FAQ
- When did the Rams and 49ers last meet on Monday Night Football?
- Oct 3, 2022: 49ers 24, Rams 9 at Levi's Stadium.
- What is the Rams' all-time Monday Night Football record against the 49ers?
- 4-8 in 12 games since 1972, from the Rams' side.
- When did the Rams last beat the 49ers on Monday Night Football?
- Dec 30, 2002: Rams 31, 49ers 20 at Edward Jones Dome.
- When did the 49ers last beat the Rams on Monday Night Football?
- Oct 3, 2022: 49ers 24, Rams 9 at Levi's Stadium.
- What is the Rams' longest Monday Night Football winning streak against the 49ers?
- 2 games, from the 1972 season through the 1974 season.
- What is the 49ers' longest Monday Night Football winning streak against the Rams?
- 4 games, from the 2014 season through the 2022 season.
More: every Rams primetime and holiday game · every 49ers primetime and holiday game · Rams 2026 schedule tools · look up another pairing
Updated: September 7, 2026 · 13,814 regular-season games in the file, 1966 to 2025