Indianapolis Colts vs. San Francisco 49ers on Sunday Night Football
The Indianapolis Colts are 1-0 against the San Francisco 49ers in regular-season Sunday Night Football games since 2021. The teams have met once on Sunday night in that span, with Indianapolis winning 1 and San Francisco winning 0.
Colts vs. 49ers Sunday Night Football record: 1-0
1-0 from the Colts’ side, 0-1 from the 49ers' side. Most recent: Oct 24, 2021, Colts 30, 49ers 18 at Levi's Stadium. Regular season only; ties count as ties.
Every Indianapolis Colts vs. San Francisco 49ers Sunday Night Football game
Newest first. The running record is the Colts’ record in these games through that date. Stadiums are listed from 2000 onward.
| Dateregular season | Matchupaway at home | Scorewinner first | Stadiumfrom 2000 | Coltsresult · running record |
|---|---|---|---|---|
| Oct 24, 2021 | Colts at 49ers | Colts 30, 49ers 18 | Levi's Stadium | W · 1-0 |
Indianapolis Colts vs. San Francisco 49ers Sunday Night Football FAQ
- When did the Colts and 49ers last meet on Sunday Night Football?
- Oct 24, 2021: Colts 30, 49ers 18 at Levi's Stadium.
- What is the Colts' all-time Sunday Night Football record against the 49ers?
- 1-0 in 1 game since 2021, from the Colts' side.
- When did the Colts last beat the 49ers on Sunday Night Football?
- Oct 24, 2021: Colts 30, 49ers 18 at Levi's Stadium.
- When did the 49ers last beat the Colts on Sunday Night Football?
- Never in these games: the 49ers are 0-1 here.
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Updated: September 7, 2026 · 13,814 regular-season games in the file, 1966 to 2025