Indianapolis Colts vs San Francisco 49ers on Sunday Night Football
The Indianapolis Colts are 1-0 on Sunday night against the San Francisco 49ers since 2021: 1 game, 1 won, 0 lost.
Indianapolis Colts vs San Francisco 49ers Sunday night record since 2021
1-0 from the Colts’ side, 0-1 from the 49ers' side. Most recent: Oct 24, 2021, Colts 30, 49ers 18 at Levi's Stadium. Regular season only; ties count as ties.
Every Colts–49ers Sunday night game
Newest first. The running record is the Colts’ record in these games through that date. Stadiums are listed from 2000 onward.
| Dateregular season | Matchupaway at home | Scorewinner first | Stadiumfrom 2000 | Coltsresult · running record |
|---|---|---|---|---|
| Oct 24, 2021 | Colts at 49ers | Colts 30, 49ers 18 | Levi's Stadium | W · 1-0 |
Indianapolis Colts vs San Francisco 49ers Sunday night FAQ
- When did the Indianapolis Colts and San Francisco 49ers last meet on Sunday night?
- Oct 24, 2021: Indianapolis Colts 30, San Francisco 49ers 18 at Levi's Stadium.
- What is the Indianapolis Colts' all-time Sunday night record against the San Francisco 49ers?
- 1-0 in 1 game since 2021, from the Indianapolis Colts' side.
- When did the Indianapolis Colts last beat the San Francisco 49ers on Sunday night?
- Oct 24, 2021: Indianapolis Colts 30, San Francisco 49ers 18 at Levi's Stadium.
- When did the San Francisco 49ers last beat the Indianapolis Colts on Sunday night?
- Never in these games: the San Francisco 49ers are 0-1 here.
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Updated: September 7, 2026 · 13,814 regular-season games in the file, 1966 to 2025