Detroit Lions vs San Francisco 49ers on Sunday Night Football
The Detroit Lions are 0-1 on Sunday night against the San Francisco 49ers since 2012: 1 game, 0 won, 1 lost.
Detroit Lions vs San Francisco 49ers Sunday night record since 2012
0-1 from the Lions’ side, 1-0 from the 49ers' side. Most recent: Sep 16, 2012, 49ers 27, Lions 19 at Candlestick Park. Regular season only; ties count as ties.
Every Lions–49ers Sunday night game
Newest first. The running record is the Lions’ record in these games through that date. Stadiums are listed from 2000 onward.
| Dateregular season | Matchupaway at home | Scorewinner first | Stadiumfrom 2000 | Lionsresult · running record |
|---|---|---|---|---|
| Sep 16, 2012 | Lions at 49ers | 49ers 27, Lions 19 | Candlestick Park | L · 0-1 |
Detroit Lions vs San Francisco 49ers Sunday night FAQ
- When did the Detroit Lions and San Francisco 49ers last meet on Sunday night?
- Sep 16, 2012: San Francisco 49ers 27, Detroit Lions 19 at Candlestick Park.
- What is the Detroit Lions' all-time Sunday night record against the San Francisco 49ers?
- 0-1 in 1 game since 2012, from the Detroit Lions' side.
- When did the Detroit Lions last beat the San Francisco 49ers on Sunday night?
- Never in these games: the Detroit Lions are 0-1 here.
- When did the San Francisco 49ers last beat the Detroit Lions on Sunday night?
- Sep 16, 2012: San Francisco 49ers 27, Detroit Lions 19 at Candlestick Park.
More: every Lions primetime and holiday game · every 49ers primetime and holiday game · Lions 2026 schedule tools · look up another pairing
Updated: September 7, 2026 · 13,814 regular-season games in the file, 1966 to 2025