Has an NFL game ever ended 41–15?

Yes. An NFL game has ended 41–15 once. The Colts beat the Bills 41–15 on November 21, 2021. It was the 1,070th different final score in NFL history.

Every NFL game that ended 41–15

Datenewest first	Winner41 points	Loser15 points	Wherehome team	Roundplayoffs	Windowstandalone game
Nov 21, 2021	Indianapolis Colts	Buffalo Bills	Bills	—	—

Scores next to 41–15

40–14 happened 18 times
40–15 happened once
40–16 happened 4 times
41–14 happened 35 times
41–16 happened 9 times
42–14 happened 29 times
42–15 happened once
42–16 happened once

Where 41–15 sits

41–15 was the 1,070th different final score in NFL history, and it first happened in 2021. The league has produced 1,097 different final scores through 18,340 games. See the whole grid →

About the data

Scorigami is a term coined by Jon Bois in 2014; his 2016 video explains the idea. Game data from nflverse and the FiveThirtyEight NFL archive: every NFL and AFL regular-season and playoff game since 1920, Super Bowls included, the AAFC and the Pro Bowl left out. Franchises carry their current name, so the Baltimore Colts count for Indianapolis and the Houston Oilers for Tennessee.

Updated: October 26, 2026